Collaboration is an essential component of multidisciplinary scientific research. We are grateful to be working with diverse teams who further our science and broaden our horizons.
At the Centre for Virus Research, we work closely with the groups of Alfredo Castello, Stephen Carter, Oya Cingoz.
We continue to explore the ubiquitin system with the Virdee Lab at the MRC Protein Phosphorylation and Ubiquitylation Unit in the University of Dundee. Satpal Virdee has developed various classes of activity based probe to monitor enzymes of the ubiquitin cascade.
We collaborate with the Clausen Lab at the Institute of Molecular Pathology in Vienna, Austria. Tim Clausen’s team are structural biologists specialising in the mechanisms of giant E3 ubiquitin ligases like HUWE1, BIRC6 and RNF213.
We are collaborating with Sam Wilson at the University of Cambridge on the mechanism of OAS2 restriction of coronaviruses.
We also collaborate with Suzannah Rihn at the University of Cambridge on the role of TCF7L1 in HIV-1 replication.
The Fletcher Lab 